The West Coast main line which connects Glasgow Central to London Euston will see tracks renewed at several locations, including Carstairs, Beattock and Symington South.
The programme of work is designed to create a more reliable and resilient railway infrastructure and will also see structural improvement works carried out at Cathcart Road in Glasgow.
The majority of the country's rail services will not be affected during this period, however, due to the complex nature of the engineering work required will mean that some short-term closures of the line will take place.
Passengers travelling between the 30th of April and the 3rd of May are being advised to plan their journeys ahead using https://www.nationalrail.co.uk or via individual rail operator's websites.
Network Rail also wishes to remind passengers of ongoing improvement works for the Argyle line which will affect services between Exhibition Centre and Rutherglen.
Liam Sumpter, Network Rail route director of Scotland, said:
“The improvement works planned for the May Bank Holiday is crucial to improving the reliability of Scotland's Railway”
“The work will help provide a more modern railway while limiting future disruption for passengers”
“We understand the inconvenience this work will cause some customers, but such a significant programme cannot be delivered without temporary disruption.”
“We would like to reassure passengers every effort has been made to reduce the impact of our activities as much as possible and we thank you for understanding.”
No wonder more engineering works is putting people off using trains including when commuting to work.